Product Introduction

Synephrine also known as a p-synephrine, which has been wildly used in medicine and healthy products like fat burner. The common form of synephrine used on the market are normally Synephrine Hcl, sometimes in combination with caffeine and other extracts like green tea extracts as a weight loss dietary supplement for oral consumption.

Synephrine is an alkaloid occurring naturally in some plants and animals. Study shows that synephrine was first isolated as a natural products from the leaves of various Citrus trees and in different citrus juices (Bitter orange). Therefore the extracts of bitter oranges also contain a higher percentage of Synephrine. Low levels of Synephrine was also found in normal human urine and in other mammalian tissue.

Effects / Benefit / Uses

Synephrine Hcl was firstly used as a synethetic drug in Europe in 1920s under the name of sympatol. It was mainly used for the treatment of of attacks of hay fever, asthma, coughing, spasms of asthma and pertussis (whooping cough).

Classical study of Synephrine Hcl shows it has effects including raising blood-pressure, dilating the pupil, and constricting peripheral blood vessels. There are also some evidence in recent studies shows Synephrine Hcl produces most of its biological effects by acting as an agonist (i.e. stimulating) at adrenergic receptors, with a distinct preference for the α1 over the α2 sub-type. However, the potency of synephrine at these receptors is relatively low. This is also the reason that lots of weight loss dietary supplement product using it as a key ingredients.

Side Effects and Dosage:

As a natural occurring alkaloid, Synephrine Hcl are likely safe for adults when taken in amount found in food or by the recommendation of doctors. The recommended dosage was consider to be 15mg-20mg per service and no more than twice a day.

Reference: http://www.webmd.com/vitamins-supplements/ingredientmono-976-bitter%20orange.aspx?activeingredientid=976

https://en.wikipedia.org/wiki/Synephrine